From 360° video to interactive virtual reality

The science of medical hypnosis is fundamentally based on the power of the imagination and the mind’s ability to visualise environments and scenarios that promote relaxation and care. Virtual reality (VR) technology offers a unique opportunity to transpose this practice into a digital environment and make it easier for patients to benefit from it.

However, unlike a traditional hypnosis session, which relies on the patient’s imagination, the VR session is based on a predefined visual and verbal guide. This difference raises a major challenge: it is essential to design VR scenarios in such a way as to remain faithful to the principles of traditional hypnosis, in both the verbal and visual elements.

In the HypnoVR medical device, we have combined hypnotic verbal support with music therapy and hypnotic visual scenarios to exploit the full potential of the total visual and auditory immersion made possible by virtual reality. This convergence between hypnosis and virtual reality offers considerable potential for innovative therapeutic approaches, particularly in pain management, stress reduction and other areas of mental and physical health.

In this article, we explore the creation of a visual scenario for HypnoVR, with the essential therapeutic elements to be integrated, as well as the challenges and opportunities linked to the evolution of headsets.

The fusion of hypnosis and virtual reality

To create an effective hypnotic experience in virtual reality, it is essential to master all the subtleties involved in a traditional hypnosis session. This requires meticulous attention to detail and an in-depth understanding of the visualisation techniques that accompany a session. The guiding principles were defined by our founders, Dr Denis Graff and Dr Chloé Chauvin, both anaesthetists and hypnopraticians.


These principles include :

a visual animation for
support the cardiac coherence exercise

immersive, soothing landscapes

strategic use of colour and pattern
that promote relaxation and concentration

textures and shapes designed
to evoke tranquillity and serenity

elements of visual focus

a move that reflects evolution
in the hypnosis course and limits boredom

symbolic and metaphorical elements
that give meaning to the experience


For the experience to be as profound and effective as possible, it is crucial to integrate these principles harmoniously and coherently into the visual scenario, in line with those of hypnosis. The aim is to guide the user towards a state of heightened receptivity, not only to the hypnotic discourse conveyed by a voice-over but also to the musical ambience (music therapy) that accompanies the experience.

Simulation or video: a look back at HypnoVR’s historic choice

HypnoVR’s fundamental objective has always been to reproduce as closely as possible the experience of a traditional hypnosis session, with the emphasis on immersion as the key factor. It is this approach that has proved so effective, with over 23 scientific papers to date. Our aim is to create a high-quality immersive experience, while complying with medical specifications to ensure maximum therapeutic effectiveness.

Faced with the complexity of meeting this need with live-action films, the structure of which would require colossal staging resources and special effects, so we opted for experiments designed by ourselves in 3D. To implement these 3D visual scenarios, we came up with two options: 360° video or real-time simulation.

View of a 3D visual scenario being designed

Why 360° Video?

The performance of standalone VR headsets played a crucial role in our development decision. Historically, their limited graphics processing power posed major challenges for the simulation of real-time environments. This meant making significant compromises either on quality and visual richness, or on the fluidity of the experience. This limitation was particularly pronounced when HypnoVR was first created in 2016.

Playing a video, even in 360° format, requires few resources but does not exploit 100% of the immersive potential of VR and limits the possible interactions with the virtual environment.

360 video proved to be the optimum solution, providing fluid, high-quality immersion despite the performance limitations of VR headsets. By creating videos from our 3D environments, we have been able to exercise complete control over the visual aspect, while guaranteeing a user experience that meets our standards, is comfortable and is adapted to the capabilities of the hardware.

The transition from 360° video to real-time simulation

In 8 years, the performance of VR headsets has improved considerably, as has our expertise in therapeutic virtual reality and our vision of the future of the product.

We are always looking to increase the therapeutic efficacy of our solutions and have identified 2 areas for development.


Improving your sense of presence

The feeling of presence helps you to step back from the real world and into a state of hypnosis. We know that improving the feeling of presence makes it easier to induce a modified state of consciousness (hypnosis) and its physiological impact (Murray, Computers in Human Behavior).

Add interactions between the patient and the virtual environment

Interactivity with the virtual world helps to control and channel the patient’s attention throughout the session.


Faced with this ambition, the video format proved to be limiting, and the arrival of the new generation of VR headsets in 2023 has changed all that. Their level of performance makes it possible to consider simulation in real time while meeting our initial requirements for quality and fluidity.

Based on several scientific publications (Hendrix, Teleoperators and Virtual Environments), we knew that real-time simulation could have a major impact on the feeling of presence that we wanted to improve. The immersive experience offered by a real-time simulation is directly enriched by the use of the stereoscopic image concept (see illustration) and sound spatialisation, offering a more realistic perception of the depth and dimensions of the virtual environment. This approach strengthens the emotional connection with the user, creating a more intense and engaging sensory immersion.

With a virtual reality experience generated in real time, it is possible to interact dynamically with the virtual environment, increasing the sense of control and involvement. This interactivity allows the experience to evolve from a passive to an active format, increasing user engagement and focusing attention.

Last but not least, there is the practical aspect of the volume of data to be stored. Unlike video, which requires a huge amount of storage space, real-time content is more compact and allows us to expand and diversify our content catalogue, offering our users more options and diversity.

By choosing real-time simulation, you are strategically moving towards a highly interactive solution capable of exploiting the full potential of the latest current and future technologies. Offering new features, enhanced capabilities and improved graphics. This choice opens the way to increasingly rich, engaging, customisable and, above all, therapeutically effective virtual experiences.

Producing scenarios in real time: from level design to technical optimisation

This transition to real-time simulation has given us the opportunity to reinvent our visual environments, injecting new creative life into them. While we’ve been keen to retain the themes of our historical scenarios, this reworking has allowed us to incorporate innovative ideas and more advanced artistic approaches, significantly enriching the aesthetic.

Forest scenario before (left) and after (right)

When reworking our scripts, it was essential to strike a balance between technical performance and visual quality. Despite the increased power of the latest generation of VR headsets, their computing capacity remains limited, requiring ingenious optimisation to enhance the experience.

HypnoVR – A tour of the “tropical beach” universe

The notion of evolution and movement is paramount in our visual scenarios and is materialised by a journey (with very slow movement to prevent motion sickness or cyber kinetosis). It’s a large environment that has to be simulated, with many visual elements to display, and this increases the problem of balancing performance and quality tenfold. Particular attention has therefore been paid to the design and layout of the environment (level design), as well as to technical optimisation.

DID YOU KNOW?

Various optimisation techniques from the world of 3D simulation are used in the design and optimisation of HypnoVR.

– Level of Detail (LOD), which adjusts the fineness of a 3D model according to its distance.

– Baking, which consists of pre-calculating the lighting effects on static objects to limit dynamic light to moving elements only.

– batching, which consists of multiplying the occurrence of a model in order to share the calculation of their rendering.

Example of batching on corals in the world of scuba diving

This work enables us to offer high-quality virtual reality experiences while exploiting the full potential of standalone VR headsets.

This experience is available as part of the HypnoVR offer with the latest generation headsets such as PICO G3 or PICO 4 Enterprise. Information is available on the product page.

Towards a new generation of interactive digital therapy

Finally, we can take the HypnoVR experience a step further and continue to increase therapeutic effectiveness with real-time simulation and the latest VR headsets. As well as improving the feeling of presence, interaction with the virtual world is now possible. However, when we talk about interactions, we need to consider them in the context of medical use, where we are trying to induce a sedative effect with VR and therefore minimise the patient’s movements.

Historical methods of interaction, using manual controllers, are unsuited to our needs because of their complexity and the physical movements required to manipulate them. However, the latest generation of headsets incorporate eye-tracking technologies that allow us to determine the position of the patient’s gaze during the virtual reality experience. This technology can be used to interpret the patient’s behaviour and dynamically adapt the session according to the patient’s attention, by triggering visual events for example, and maximise the patient’s concentration during the hypnosis session.

Real-time simulation is also at the heart of our next solution, HypnoVR Biofeedback, which uses sensors on the patient to adapt the hypnosis session according to certain physiological constants. Whether it’s adjusting the cardiac coherence exercise or triggering specific events in VR depending on the patient’s comfort, HypnoVR Biofeedback will enable a much higher level of interactivity.

Real-time simulation offers fascinating prospects for HypnoVR. This evolution allows us to explore new possibilities, merging the latest technological innovations with the unique needs of the medical sector, and pushing back the boundaries of what we can offer in digital healthcare.

Augustin Darre, lead developer & Jordan Rous, lead 3D artist

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HypnoVR acquires Oncomfort

This strategic takeover confirms HypnoVR’s position as Europe’s leading provider of virtual reality-based digital therapies to treat pain and anxiety, with solutions deployed in more than 550 hospitals

Synergies with Oncomfort will broaden HypnoVR’s product range, expand its client base and strengthen its patent portfolio, as well as providing a firm foothold in Belgium

HypnoVR plans to increase its European and international presence with the market release of second generation machine learning-based biofeedback digital therapies in 2024



Strasbourg, France, October 4, 2023 – HypnoVR, pioneer and European leader in digital therapies to manage pain and anxiety, today announces it has acquired Belgian company Oncomfort, the inventor of Digital Sedation™, a pharmacological method of relieving patients’ pain and anxiety. The financial terms of the agreement have not been disclosed.

HypnoVR strengthens its presence in digital therapies in Europe

This acquisition strengthens HypnoVR’s position as the European leader in digital therapies for pain and anxiety and should speed up the commercial roll-out of its solutions in Europe. Over 550 European healthcare facilities are now using HypnoVR technology, including more than one hundred in Belgium. A total of 200,000 patients have already been treated using its digital therapies that include a software and a VR headset. The company has the most advanced clinical validation in its field, with more than fifty clinical trials having demonstrated the efficacy of the HypnoVR and Oncomfort therapies to manage pain and anxiety, reduce medication use and improve the care pathway.

“The Oncomfort acquisition is a highly strategic step for HypnoVR that reinforces our position as the European leader in digital therapies to treat pain and anxiety and provides an ever-increasing number of healthcare facilities and patients with access to these advanced technologies. Our vision is one that Oncomfort shares, based on the clinical validity of digital therapeutic solutions and the potential of technology to deliver them to as many people as possible. HypnoVR pioneered the development and roll-out of virtual reality-based medical hypnosis solutions in France and Europe, and we intend to ramp up this work on an international scale,”said Nicolas Schaettel, president and co-founder of HypnoVR.

A strategic union with a shared vision

Oncomfort was founded in 2017 to develop Digital Sedation™, an innovative medical device combining the capabilities of virtual reality with expertise in medical hypnosis. Digital Sedation™ is a CE-marked product designed to offer patients an alternative or supplementary treatment to drugs, for managing pain and anxiety.

“Both HypnoVR and Oncomfort are pioneering companies in digital sedation and have been built on shared values, scientific validation and strict adherence to regulations to ensure compliance with the requirements for digital medical devices. I firmly believe that our acquisition by HypnoVR will create worthwhile collaborations to help healthcare professionals go further in adopting this solution as the standard of care for relieving pain and anxiety, benefiting a growing number of patients,”said Diane Jooris, founder of Oncomfort.

HypnoVR has a subsidiary in Basel, Switzerland and has just opened an office in Belgium, where a number of Oncomfort staff will be based.

The future of digital therapies: HypnoVR focuses oninnovation and biofeedback

HypnoVR has advanced, ambitious R&D projects in progress, including the development of a next-generation therapeutic virtual reality solution with biofeedback. This system offers a real-time virtual hypnosedation session adapted to the patient’s physiological condition. Patents are being filed to protect its intellectual property.


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Many facilities are already using HypnoVR to enhance their patients’ care experience.

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HYPNOVR and MDOLORIS MEDICAL SYSTEMS an innovative partnership for digital therapy

HypnoVR, the leader in virtual reality medical hypnosis, and Mdoloris Medical Systems, the leader in continuous, non-invasive monitoring of the parasympathetic system, have joined forces to develop the next generation of therapeutic virtual reality for pain and anxiety management. The HypnoVR solution integrates Mdoloris Medical Systems’ ANI (Analgesia Nociception Index) technology, which enables real-time measurement of the nervous system activity of hospitalised patients. A partnership that, for the first time in the world, combines digital therapy with real-time monitoring of the patient’s condition to offer a personalised treatment for pain and anxiety.

Launched on the digital therapy market in 2016 and now used daily by more than 280 hospitals, HypnoVR digital therapy has been proven to reduce patients’ anxiety and pain before, during and after medical procedures, also helping to reduce the use of sedatives and thus lower the risk of complications. Validated by more than 17 clinical studies (www.hypnovr.io/recherche), HypnoVR’s digital therapy is based on a purely scientific approach coupled with a dynamic of innovation thanks to the involvement of experts from the medical and digital world.

HypnoVR partners with Mdoloris Medical Systems to take its hypnotherapy solution a step further and significantly improve the control of care in a non-invasive and non-drug way. This partnership is above all the association of two experts in pain and anxiety: HypnoVR for their treatment and Mdoloris for their measurement.


As a result of their joint work, HypnoVR is launching the first HypnoVR Biofeedback prototype incorporating the latest MDoloris technology, the ANI GUARDIAN, which captures, analyses and reports nervous system responses to pain and anxiety in real time. “We are delighted to announce this OEM integration in this niche segment where few companies have a proven track record. This partnership with HypnoVR proves once again the efficiency and accuracy of the technology developed by Mdoloris Medical, which will allow to adapt and personalise the hypnosis process provided by HypnoVR. A partnership that will benefit patients first”, says Fabien Pagniez, CEO of Mdoloris Medical Systems.


This prototype is the result of 3 years of research (1 thesis, 2 scientific papers) conducted by HypnoVR in collaboration with three CNRS laboratories: the Laboratory of Engineering, Computer Science and Imaging (ICUBE), the Centre for Neurocognitive and Neurophysiological Investigation (CI2N) and the Institute of Cellular and Integrative Neurosciences (INCI) (winning research project of the iNOV national innovation competition).

The Mdoloris ANI is the chosen physiological biomarker because of its performance, recognition and validation by numerous studies. The HypnoVR Biofeedback product is therefore the result of a partnership between 2 startups in the French ecosystem. True to its innovative DNA, HypnoVR is proud to launch the first version of this new prototype – HypnoVR Biofeedback – delivering therapeutic virtual reality that adapts to the patient’s condition in real time. It will allow better management of pain and anxiety during medical interventions depending on the patient. “As discovery-driven, science-based companies, our partnership represents a unique opportunity to develop the next generation of digital therapies and continue to create the medical world of the future,” says Nicolas Schaettel, CEO of HypnoVR.


About HypnoVR HypnoVR specialises in the development of digital therapies combining medical hypnosis and virtual reality for pain and stress management. It designs, develops and markets software applications and medical devices as innovative hypnosedation tools to improve the quality of care and patient comfort. HypnoVR’s solutions help to improve care throughout the patient journey. They can be used in a wide range of medical specialties, including anaesthesia and intensive care, surgery, dental care and medical imaging. The company is certified according to ISO 13485:2016 since April 2021. Founded in Strasbourg, France, in 2016 by anaesthetists and hypnotherapists Dr Denis Graff and Dr Chloé Chauvin, and entrepreneur Nicolas Schaettel.
About Mdoloris Medical System MDoloris Medical Systems, a French venture capital company, is the first company in the world to be able to provide clinicians with medical devices for continuous, non-invasive monitoring of patient parasympathetic tone. MDoloris is present in more than 78 countries and has equipped more than 3,000 teaching hospitals and more than 400,000 patients have benefited from medical follow-up. With already 3 official OEM partnerships (Minray, Masimo and HypnoVR) Mdoloris is considered as the leader in real time measurement of the nervous system.
About ANI technology ANI is a parameter derived from heart rate variability that helps clinicians assess the autonomic nervous system, which guides them in the management of analgesics during surgery and anaesthesia. This improves postoperative pain, PONV scores, shivering scores, and reduces postoperative opioid use, as well as reducing hospital stays and may reduce values on the Montreal Scale, a scale used to assess postoperative cognitive impairment. This new physiological parameter also makes it possible to address the level of well-being of non-communicative patients.

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More than 300 institutions are already using HypnoVR to improve their patients’ experience of care.

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Music therapy: a recognised practice in the management of pain and anxiety

Music therapy is a care practice that uses music, sounds and rhythms as therapeutic tools for psychological, sensory and neurological disorders. This safe and effective non-medicinal therapy is of great importance in the management of pain and anxiety. It is also beneficial to the well-being and quality of patient care, especially when combined with other non-drug therapies such as virtual reality therapy.

What is Music Therapy?

In the first place, as far back as antiquity, the benefits of music therapy on the soul or on mood have been studied using various instruments, rhythms and sounds. Then, the modern history of music therapy begins in the 1940s-50s. This new form of therapy is then proposed to relieve soldiers suffering from post-traumatic stress disorder.

Initially reserved for psychotherapy, the therapeutic aims of music therapy have been greatly expanded, particularly in relation to pain, stress and anxiety. Music therapy is part of a care programme (surgery, nursing care, medical imaging, etc.) and is aimed at all populations (children, adolescents, adults, the elderly).


More than a hundred studies highlight the value of music therapy in the treatment of pain and anxiety. In addition to a physiological effect on haemodynamic (cardiac deceleration) and ventilatory constants, a psychological effect by encouraging listening has also been demonstrated. Musical harmony, created by the variation of rhythms, sounds and melodies, leads to a decrease in cortisol levels, a release of endorphins, serotonin and dopamine. These actions are accompanied by a significant decrease in the consumption of anxiolytics and antidepressants.

-14%

anxiety by listening to music

read more

Kühlmann’s meta-analysis showed that listening to music during surgery significantly reduced perioperative anxiety and pain in adult patients. These beneficial effects have also been observed in patients before and after general anaesthesia, demonstrating the ability of music to increase brain plasticity and cause changes in synaptic connections.

Music therapy can use a wide range of techniques to make the experience as effective and enjoyable as possible. These techniques include the variation of the instrumental richness, rhythm or frequency of the sounds, which allow for the creation of a musical journey that accompanies the patient in different phases. The structure of a music therapy composition is referred to as a U-shaped sequence, when the construction of the composition gradually guides the patient into a state of relaxation and then back into a state of alertness.

Combining music therapy
to therapeutic virtual reality

In the case of therapeutic virtual reality, music therapy is one of the three pillars of the experience. This is combined with verbal support and visual immersion in a virtual reality headset.

The originality of HypnoVR’s approach is based on the know-how and experience of medical hypnosis applied to virtual reality technology. The three parameters “music, voice and image”, whatever their combination, have been specifically developed to be synergistic in order to always offer the best immersion and therapeutic effectiveness.


The architecture of the musical compositions was thus created from a demanding set of specifications defined to support the medical hypnosis session. A collective of seven professional musicians was asked to compose the melodies. They all hold a postgraduate diploma in musical composition from the Conservatoire national supérieur de musique et de danse de Paris.

What architecture for HypnoVR music compositions?

These musicians composed 12 musical themes in four different styles: classical music, electronic music, acoustic music and world music. Each style has three different musical themes of about 30 minutes each. As a result, any patient can identify a familiar theme in the panel of musical compositions, adapted to their affinities, to maximise the comfort and immersion of the session.

The architecture of the musical compositions is structured in a U-shaped sequence, with proven therapeutic effectiveness. The session starts at a fast, stimulating pace and includes a rich instrumentalisation. It continues with a progressive and imperceptible lightening of the orchestration, a slowing down of the rhythm and an adaptation of the sound intensity in coherence with the hypnotic text and the path in the immersive visual environment (descending phase of U).

What happens during a HypnoVR session

This musical accompaniment of the patient, in synergy with the hypnotic words and dreamlike visual worlds, gradually takes the patient into a state of deep and hypnotic relaxation. At the end of the session, the patient is invited to reconnect with his or her environment, to re-synchronise with the ‘here and now’ and to benefit from a new energy. In this sequence, the musical theme is gradually fleshed out with increasingly rich instrumentation and orchestration. The volume increases and the pace quickens to accompany the return to wakefulness. We are in the ascending phase of the U.

The phases of the musical compositions are in total coherence with the different sequences of the visual path and the stages of the hypnotic accompaniment. The aim is to obtain a synergy between the stimulation of visual, sound and musical sensory capacities, whose therapeutic effectiveness exceeds that of a mono-sensory stimulation.

he global therapeutic approach,
according to HypnoVR

In the HypnoVR experience, the musical environment, the hypnotic verbal accompaniment and the immersion in a dreamlike visual universe constitute the 3 pillars of digital therapy. These 3 elements are specifically designed to exploit the full potential of therapeutic virtual reality.

Verbal support

The virtual route

The musical atmosphere

The verbal support, the central element of the session, consists of a hypnotic speech. They are designed by Chloé Chauvin and Denis Graff, anaesthetists, specialists in pain management, experienced hypnopractors and co-founders of HypnoVR. They follow the structure of a medical hypnosis session and are consistent with the patient’s immersive visual journey.

The software offers a choice of fifteen different texts, which can be adapted to as many therapeutic indications as durations.

The visual world is designed as a calm and soothing virtual evolutionary journey in which the patient progresses through pleasant discoveries, encouraging a gradual letting go, in phase with the hypnotic text. The speed, light intensity and colour range are specifically calibrated during the session to focus the patient’s attention and support the hypnotic process.

Unique and customisable sessions

The variety of musical themes, the variety of visual themes and the multiplicity of texts make it possible to adapt the session to the patient and the symptom to be treated. The overall experience is unique and customisable, with over 21,000 possible scenarios.

This high level of personalisation combined with the high immersive effect and U-shaped architecture of the music therapy compositions allows the patient to experience an effective and satisfying session as part of their care pathway, whether in a hospital or doctor’s surgery.

The HypnoVR solution, developed on a solid scientific basis, certified and clinically validated, is an effective non-medicinal solution for pain and anxiety. It is devoid of the side effects of anxiolytics and analgesics and can be easily integrated into any care programme without loss of time for carers.

-58%

anxiety in the context of dressing repairs
Read more

-45%

Morphine use in scoliosis surgery

Read more

Many patients

already benefit from HypnoVR

Anxiety

HypnoVR dans les cliniques dentaires Ardentis

Anxiety

La « VR », leurre contre la douleur au CHU de Poitiers

Anaesthesia

Hypno thérapie virtuelle dans le service de réanimation et surveillance continue pédiatrique

Anaesthesia

La solution HypnoVR dans le service d’oncologie du Groupe Hospitalier de Saint Vincent

Anxiety

HypnoVR soothes cancer patients: a new approach to well-being in oncology and chemotherapy!

Anxiety

Improving patient care in the operating theatre

Urgences

Digital therapy to reduce pain and anxiety over invasive procedures

Surgery

Virtual reality medical hypnosis in digestive surgery 

Anaesthesia

Shoulder surgery under locoregional anaesthesia alone and virtual reality headset

Surgery

HypnoVR on a 100 year old patient

Anaesthesia

HypnoVR innovation in endoscopy  

Surgery

Soothing patients and relieving carers at Besançon University Hospital

Dental care

Therapeutic virtual reality in dentistry

Dental care

HypnoVR at the dentist

oncology

HypnoVR at the service of well-being for patients

Imaging

Hypnosis under virtual reality in interventional radiology at the Clinique du Parc

Surgery

Reducing stress and anxiety in the operating theatre thanks to HypnoVR

Anaesthesia

Hands chirurgy & HypnoVR for the well-being of the patient

Surgery

Varicose surgery with HypnoVR

Surgery

Hypnoanalgesia to improve patient comfort

Imaging

Virtual reality is now available to relax patients during MRI

Anaesthesia

HypnoVR in the operating theatre at Montauban Hospital

oncology

Virtual reality helmets for treating pain

oncology

HypnoVR for the comfort of children during treatment

Surgery

Abdominal aortic aneurysm and medical hypnosis

Gynaecology

Virtual reality in the maternity unit is a reality

Sources

  1. 1. Kühlmann AYR, de Rooij A, Kroesse LFD, et al. Meta-analysis evaluating music interventions for anxiety and pain in surgery. Br J Surg 2018;105:773-83
  2. 2. Hole J, Hirsch M, Ball E, Meads C. Music as an aid for postoperative recovery in adults: a systematic review and meta-analysis. Lancet 2015;386:1659-71;
  3. 3. Kekecs Z, Nagy T, Varga K. The effectiveness of suggestive technique in reducing postoperative side effects: a meta-analysis of randomized controlled trials. Anesth Analg 2014;119:1407-19

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More than 300 institutions are already using HypnoVR to improve their patients’ experience of care.

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No cyberkinetosis for HypnoVR users

What is cyberkinetosis?

Cyberkinetosis is the motion sickness specific to virtual reality (VR) headset technology. Discomfort, sweating, drowsiness, migraine, and even nausea are symptoms related to this state of discomfort that can be experienced by a VR headset user. Pour expliquer cela, la théorie du conflit sensoriel est celle qui a le plus de sens : cette situation se produit lorsque les informations sensorielles sont contradictoires (divergence entre les systèmes oculaire et vestibulaire), que les sens ne reçoivent pas le retour habituel auquel le patient s’attendrait, et que le patient est donc désorienté. This lack of synchronisation is known in medical circles as “cyberkinetosis”.

This condition, which is often associated with travel sickness, can therefore affect an individual using virtual reality. However, it is not systematic, cyberkinetosis varies according to 3 basic aspects:

  • the hardware

  • The VR universe

  • Patient’s feelings

Overall, therapeutic VR is associated with a low incidence of side effects ranging from 0 to 9.5%. However, to eliminate sensory conflict in VR, it is necessary to restore harmony between the body’s visual and vestibular systems so that users can experience immersive, safe and comfortable VR. This is because cyberkinetosis is not related to the notion of movement but to an inconsistency between the movement and the feeling of that movement.

Cyberkinetosis and the HypnoVR medical device

With HypnoVR, cyberkinetosis is almost non-existent and represents only 1.6% of healthy users (including nausea 0.8%), and 3% in patients who used HypnoVR during surgery or medical procedures (3 studies in adults and 1 in children did not find nausea)

In a postoperative study of major surgery with high doses of morphine, the use of HypnoVR in addition to analgesics resulted in a decrease in postoperative vomiting compared to analgesics alone.

These results obtained with HypnoVR should be compared with the results in the literature. The incidence of nausea/vomiting in surgery is approximately 30%. It is of multifactorial origin, linked to the patient, the type of anaesthesia and the analgesics, particularly morphine.

Our experience is thus specifically designed to integrate the techniques of a traditional medical hypnosis session with the quality of the architecture and sensory coherence of the proposed experience.

The very low rate of nausea observed with the HypnoVR headset in this intraoperative context is a testament to the quality of the architecture and the sensory coherence of the proposed experience. We thus ensure optimal comfort of use while integrating the hypnotic mechanisms useful for therapeutic effectiveness.

HypnoVR obtains ISO 13485 certification

Strasbourg, 14 April 2021, HypnoVR, the European leader in digital therapies for pain and stress management, announces that it has obtained its certificate of conformity to ISO 13485:2016 from the notified body MDC. HypnoVR thus becomes the first company to be certified in its field with its virtual reality medical hypnosis solution.

“Obtaining ISO 13485:2016 certification represents a new key step for HypnoVR as a medical device manufacturer. This certification reinforces the quality management process we have put in place and which is essential to evolve within the regulatory framework of healthcare. This demanding certification also underlines the evolution of the company, which now meets the highest levels of performance, quality and safety. With this certification, we continue to make HypnoVR a reference in the non-drug treatment of pain and anxiety,” says Nicolas Schaettel, co-founder and president of HypnoVR.

Already widely present in anaesthesia and the operating theatre, HypnoVR is constantly developing new applications of its digital therapy for the medical world. HypnoVR software is used beyond the operating theatre in many departments to reduce patient pain and anxiety, but also to manage caregiver stress, with clinically validated therapeutic effectiveness. This certification supports the potential of the solution and broadens the prospects for growth in France and internationally.

“The ISO certification is a real recognition of the investment of the whole team in the structuring of our activity. In addition to being internationally recognised, it is essential for the design of a safe and effective medical device” explain Drs Chloé Chauvin and Denis Graff, co-founders of HypnoVR.

Virtual reality medical hypnosis session in the operating theatre, digital therapy to reduce pain, stress and anxiety

About ISO 13485: 2016

The internationally recognised ISO 13485:2016 standard sets out the requirements for a quality management system specific to the medical device sector.

In the face of regulations that impose increasingly stringent requirements at every stage of a product’s life cycle, including service and delivery. ISO 13485:2016 enables organisations to demonstrate the effectiveness of their quality management processes and implement best practice throughout their operations.

Qualcomm XR

HypnoVR is the first French company to join the Qualcomm XR program!

It will allow us to accelerate the deployment of our innovations based on virtual reality!

The development of our solution, based on our scientific advances and the evolution of digital technologies, is one of our priorities in order to offer an increasingly accessible and professional experience.

Also supported by Pico Interactive , Oculus VR and Microsoft for Startups Europe, the resources and expertise provided by our technology partners help us integrate the latest cutting-edge software and hardware technologies into our experience.

JANUARY Consummer Electronic Show 2019, Innovation Award 2019 catégories VR

Selected by the CTA (the Consumer Technology Association) and supported by the Grand Est Region, the Innovations Awards reward the best French innovations that will be presented from 8 to 12 January 2019 at the CES show in Las Vegas. HypnoVR was awarded the innovation prize in the “virtual reality” category by a jury of high-tech professionals.

FEBRUARYLes Trophées du Bien-être , Trophée Santé 2019

Each year, the Trophées du Bien-être reward a medical innovation, a gesture, an action, a play, a film, a concert, a music, an everyday product, or an urban improvement that has contributed to creating well-being for the greatest number of people. HypnoVR wins in the Health category.

FEBRUARY La Tribune, 10.000 startups pour changer le monde, Lauréat régional du concours 10 000 startups pour changer le mondecatégorie Start

Organised by La Tribune and BNP Paribas, the 10,000 startups to change the world competition rewards a startup in five categories “Environment & Energy”, “Deep tech & Data”, “Smart tech”, “Health” and “Start”. HypnoVR regional winner in the Start category.

MARCH 5 ème édition du E-HealthWorld Monaco, Grand Prix Innovation Anesthésie et Prix Spécial Visiomed 2019

E-HealthWorld Monaco is a congress dedicated to connected health and the medicine of tomorrow and organised by health professionals. Sponsored by prestigious official, institutional and private partners, and supported by extensive media coverage, #eHM brings together e-health professionals. HypnoVR Grand Prix Innovation in Anaesthesia

MARCH Confiance de l’Association Autrement

An association that has been involved with patients suffering from pain and/or serious illnesses for 15 years. Its mission: To relieve Acompany Support. The association has collected donations to improve the care of seriously ill patients through various complementary medicines including the HypnoVR device. A real pride for our company.

APRIL Confiance de l’Association Coeur à Choeur

Coeur à Choeur is a non-profit association of parents of sick children. The association regularly organises gospel concerts and donates the profits from the concerts to needy families, specialised structures or associations for the disabled. We are very grateful to have been chosen to help alleviate the suffering of sick children in the paediatric intensive care unit of the Hautepierre Hospital. An initiative also supported by the Association Une note de douceur.


MAY Congrès de l’Association Française de Chirurgie, Prix de l’Innovation du Jury 2019

Organised by the French Association of Surgery (AFC), the Creation and Innovation competition rewards the best innovations of the congress thanks to the votes of the participating surgeons. Public Innovation Award in 2018, HypnoVR has the honour of being the Jury’s Innovation Award for this 2019 edition.

MAY Vivatech 2019, Orange concours de pitch Challenge 5G,Finaliste

Organised by Orange on the Orange Lab stand at Vivatech 2019, the annual event dedicated to technological innovation and start-ups. The objective of the challenge: to demonstrate to Orange, the jury and the public how Orange’s 5G will help redefine and enhance their product and service offering. HypnoVR among the 5 finalists out of 280 applications.

MAY Paris HealthCare Week HIT Innovations Trophées 2019,Finaliste catégorie traitement et éducation thérapeutique

The aim is to reward the most innovative professionals and companies in the sector of new technologies applied to health. HypnoVR was a finalist in this first edition in the treatment and therapeutic education category.

MAY Confiance de l’association Lulucémie

Lulukaemia is an association whose aim is to raise awareness of leukaemia and to help the nursing staff by collecting donations. Lulukemia has thus enabled the financing of several HypnoVR devices for the Centre Hospitalier de la Côte Basque. HypnoVR is very proud to be able to contribute to relieving stress and anxiety during chemotherapy and to reduce the side effects of chemotherapy alongside the health care team thanks to this great association.

SEPTEMBER The Eurometropole of Strasbourg is the winner of the call for projects launched by the State, “Territoires d’Innovation”, on the theme of health.
Winner of this call for projects, whose operator is the Caisse des Dépôts, allows for the financing of nearly €13 million in subsidies and more than €24 million in equity investments in companies, but above all to become a reference territory in France for health. HypnoVR is proud and grateful to be part of the project companies.

OCTOBER Confiance de l’Association de La Ligue Contre le Cancer

The League against Cancer, an association that finances research, prevents risks and supports patients and their families, together with the Pony Pony Run Run association, have financed a HypnoVR device for the Jean Perrin Centre in Clermont-Ferrand. Intended for patients to reduce pain and anxiety related to certain care in the Paediatric Haematology and Oncology, Adult Clinical Haematology and Pneumology departments. It is a great honour to have the confidence of such an important and publicly recognised organisation.

OCTOBER Journées Francophones de la Société Française de Radiologie – SFR, Coup de Cœur de l’Innovation en imagerie médicale

Each year, the French Society of Radiology awards numerous prizes and grants, including the “Coup de cœur” innovation prize during the Journées Francophones de la Société Française de Radiologie in Paris. HypnoVR Coup de Coeur for innovation in medical imaging, an award that will allow HypnoVR to be automatically present on a stand at the 2020 edition.

OCTOBER HypnoVR certifiée Jeune Entreprise Innovante

HypnoVR certified as a Young Innovative Company. This new status will allow our young company to accelerate its research projects and develop the use of HypnoVR in the treatment of pain and anxiety in as many indications as possible.

NOVEMBER Partenariat Vivalto Santé / HypnoVR

HypnoVR, a French start-up specialising in the development of medical hypnosis solutions using virtual reality, and the Vivalto Santé Group, the third largest player in the private hospital sector in France, have announced the signing of a major agreement in three areas: the distribution of HypnoVR software, clinical research and co-development.

NOVEMBER VIRTUALITY, Virtuality XR Awards 2019, Best Project for the Health Industry

Each year the Virtuality XR Awards reward the best achievements in virtual reality, augmented reality, holograms etc. in industrial and creative categories. HypnoVR voted Virtuality XR Awards in the Health Industry category.

NOVEMBER Partenariat Pierre Fabre Oral Care / HypnoVR

HypnoVR: the first medical hypnosis solution using virtual reality to reduce patient anxiety during care. On the occasion of the annual congress of the French Dental Association (ADF), Pierre Fabre Oral Care, leader in oral hygiene in pharmacies, and HypnoVR, a French start-up specialising in the development of medical hypnosis solutions using virtual reality, have announced the signing of a partnership with a view to offering dental surgeons HypnoVR©, an innovative device for treating stress and anxiety in the treatment room.

Join the movement!

More than 300 institutions are already using HypnoVR to improve their patients’ experience of care.

BFM Life – Sunday 19 January

Pr Eric Vibert, liver surgeon and director of the BOPA Innovation Chair at APHP, Dr Philippe Bencteux, president and founder of Robocath, Nicolas Pivert, director of the cardiovascular unit of Medtronic France, and Denis Graff, anaesthetist, hypnosis practitioner and co-founder of Hypno VR, were guests on the BFM Life programme presented by Julien Gagliardi and Lorraine Goumot

HypnoVR passage: 1h10 – 1h23

Watch the programme: https://bfmbusiness.bfmtv.com/mediaplayer/video/bfm-life-dimanche-19-janvier-1216027.html

Join the movement!

More than 300 institutions are already using HypnoVR to improve their patients’ experience of care.

Full article:

http://www.leparisien.fr/seine-maritime-76/des-casques-de-realite-virtuelle-pour-traiter-la-douleur-au-chu-de-rouen-20-02-2020-8263647.php

Join the movement!

More than 300 institutions are already using HypnoVR to improve their patients’ experience of care.